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Clinical trials for Aminolevulinic Acid

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   43895   clinical trials with a EudraCT protocol, of which   7301   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    38 result(s) found for: Aminolevulinic Acid. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2006-000314-20 Sponsor Protocol Number: ALA-AK-CT001 Start Date*: 2006-09-26
    Sponsor Name:Biofrontera Bioscience GmbH
    Full Title: A randomized placebo-controlled clinical trial of topical photodynamic therapy with a nanoemulsion formulation of 5-aminolevulinic acid for the treatment of actinic keratosis
    Medical condition: actinic keratosis (AK)
    Disease: Version SOC Term Classification Code Term Level
    10000614
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-000096-21 Sponsor Protocol Number: NXDC-MEN-301 Start Date*: 2020-08-04
    Sponsor Name:NX Development Corp.
    Full Title: A Phase 3 Multicenter Study of Gleolan (Aminolevulinic Acid Hydrochloride) to Enhance Visualization of Tumor in Patients with Newly Diagnosed or Recurrent Meningiomas
    Medical condition: Meningioma
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10027191 Meningioma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004258-26 Sponsor Protocol Number: 02_2004 Start Date*: 2005-06-23
    Sponsor Name:University Clinic of Dermatology Division of Special and Enviromental Dermatology
    Full Title: Photodynamic Therapy (PDT) vs Chemopeeling for the treatment of multiple actinic keratoses on the underarms
    Medical condition: Actinic Keratosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-003230-32 Sponsor Protocol Number: 5-ALA_Meningiomas Start Date*: 2015-11-17
    Sponsor Name:Medizinische Universität Graz
    Full Title: The use of 5-aminolevulinic acid (gliolan) mediated protoporphyrin IX fluorescence to label neighbouring infiltration zones in meningiomas
    Medical condition: Surgical candidates with supratentorial meningiomas
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004959-23 Sponsor Protocol Number: NPJ005-DM2-0521 Start Date*: 2018-07-05
    Sponsor Name:neopharma Japan Co., Ltd
    Full Title: A 24-week, Phase IIa, Double blind, Randomized, Parallel Group, Placebo controlled, Exploratory Study to Evaluate the Efficacy and Safety of 5 Aminolevulinic Acid Co-administered with Sodium Ferrou...
    Medical condition: Type 2 Diabetes Mellitus in Patients who have not Achieved Adequate Glycemic Control with Maximum Tolerated Dose of Metformin Daily or Sulfonylurea
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2017-004944-39 Sponsor Protocol Number: NPJ005-DM2-0522 Start Date*: 2018-04-27
    Sponsor Name:neopharma Japan Co., Ltd
    Full Title: A 24 Week, Phase IIa, Double blind, Randomized, Parallel Group, Placebo-controlled, Proof of Concept Study to Assess the Efficacy and Safety of Two Doses of 5 Aminolevulinic Acid Co-administered wi...
    Medical condition: Type 2 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) HU (Completed) PL (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2011-005809-77 Sponsor Protocol Number: NL38217 Start Date*: 2013-01-31
    Sponsor Name:Maastricht University Medical Centre
    Full Title: Treatment of superficial basal cell carcinoma by topical photodynamic therapy with fractionated 5-aminolevulinic acid 20% versus two stage topical photodynamic therapy with methylaminolevulinate
    Medical condition: Superficial basal cell carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001440-38 Sponsor Protocol Number: 42647 Start Date*: 2014-05-22
    Sponsor Name:Department of Dermatology D92, Bispebjerg Hospital
    Full Title: Methods to increase PpIX formation in the skin of healthy volunteers
    Medical condition: Healthy volunteers - no medical condition is investigated but pharmaco kinetics
    Disease: Version SOC Term Classification Code Term Level
    17.0 10022891 - Investigations 10040879 Skin investigations HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004760-31 Sponsor Protocol Number: CG/7657 Start Date*: 2007-04-17
    Sponsor Name:University of Dundee
    Full Title: Role and efficacy of topical 5-Aminolevulinic Acid (5-ALA) in Photodynamic detection (PDD) in determining malignant potential of oral lichen planus
    Medical condition: Oral Lichen Planus
    Disease: Version SOC Term Classification Code Term Level
    8.1 10030983 Oral lichen planus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-002432-17 Sponsor Protocol Number: ALN-AS1-003 Start Date*: 2017-11-22
    Sponsor Name:Alnylam Pharmaceuticals, Inc.
    Full Title: ENVISION: A Phase 3 Randomized, Double-blind, Placebo-controlled Multicenter Study with an Open-label Extension to Evaluate the Efficacy and Safety of Givosiran in Patients with Acute Hepatic Porph...
    Medical condition: Acute Hepatic Porphyrias (AHP)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10036182 Porphyria acute PT
    20.0 10010331 - Congenital, familial and genetic disorders 10036184 Porphyria hepatic LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) ES (Completed) DK (Completed) CZ (Completed) SE (Completed) BG (Completed) FI (Completed) BE (Completed) FR (Completed) PL (Completed) NL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-001949-15 Sponsor Protocol Number: AK 02 Start Date*: 2005-01-14
    Sponsor Name:photonamic GmbH & Co. KG
    Full Title: PD P 506 A applied for 0.5, 1, 2 or 4 hours in combination with red light for photodynamic therapy of mild to moderate actinic keratosis
    Medical condition: Actinic keratosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003555-13 Sponsor Protocol Number: AK 03 Start Date*: 2006-03-10
    Sponsor Name:photonamic GmbH & Co. KG
    Full Title: PD P 506 A or its placebo in combination with red light for photodynamic therapy of mild to moderate actinic keratosis
    Medical condition: Actinic keratosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003556-36 Sponsor Protocol Number: AK 04 Start Date*: 2006-03-10
    Sponsor Name:photonamic GmbH & Co. KG
    Full Title: Photodynamic Therapy with PD P 506 A or its placebo compared with cryosurgery for the treatment of mild to moderate actinic keratosis
    Medical condition: Actinic Keratosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-000265-32 Sponsor Protocol Number: Q282dnro3/2015 Start Date*: 2015-04-08
    Sponsor Name:Janne Räsänen
    Full Title: Daylight photodynamic therapy for actinic keratoses: a multicentre study comparing two photosensitizers (BF-200 ALA versus MAL)
    Medical condition: Actinic keratosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002746-50 Sponsor Protocol Number: Q272dnro47/2014 Start Date*: 2014-09-19
    Sponsor Name:Mari Salmivuori
    Full Title: Superficial basal cell cancer's photodynamic therapy: comparing three photosensitises: hexylaminolevulinate versus methylaminolevulinate and aminolevulinic acid nano emulsion versus methylaminolev...
    Medical condition: Superficial basal cell carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002408-97 Sponsor Protocol Number: MALvsALA Start Date*: 2015-12-16
    Sponsor Name:Dr. Carlos Serra
    Full Title: Comparative Study, intraindividual to evaluate efficacy and safety of the treatment of actinic keratosis with photodinamic therapy between methyl aminolevulinate cream and aminolevulinic acid nanos...
    Medical condition: Actinic Keratosis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10040785 - Skin and subcutaneous tissue disorders 10000614 Actinic keratosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2014-001493-34 Sponsor Protocol Number: OM01 Start Date*: 2014-12-02
    Sponsor Name:photonamic GmbH & Co. KG
    Full Title: Evaluation of the suitability of PD P 506 A in the photodynamic therapy of Distal Subungual Onychomycosis (DSO) of the great toenail.
    Medical condition: Onychomycosis (OM) is a chronic fungal infection of the finger- or toenails and one of the commonest dermatological conditions. It accounts for one third of fungal skin infections and constitutes a...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005838-19 Sponsor Protocol Number: 2011.697 Start Date*: 2012-12-28
    Sponsor Name:Hospics Civils de Lyon
    Full Title: MEDICO-ECONOMIC EVALUATION OF SURGERY GUIDED BY FLUORESCENCE FOR THE OPTIMIZATION OF THE RESECTION OF GLIOBLASTOMAS - THE RESECT STUDY
    Medical condition: Glioblastoma
    Disease: Version SOC Term Classification Code Term Level
    19.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10018336 Glioblastoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005528-15 Sponsor Protocol Number: BRD/05/059 Start Date*: 2006-01-20
    Sponsor Name:University College London
    Full Title: A RANDOMISED CONTROLLED TRIAL TO STUDY THE SIDE EFFECT PROFILE AND TO ESTABLISH MEASURES OF EFFICACY USING PHOTOFRIN OR 5 AMINOLAEVULINIC ACID PHOTODYNAMIC THERAPY IN THE ERADICATION OF DYSPLASIA I...
    Medical condition: High Grade Dysplasia in Barrett's Oesophagus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-004397-96 Sponsor Protocol Number: CF20112018 Start Date*: 2019-04-09
    Sponsor Name:Merete Hædersdal
    Full Title: Impact of thermo-mechanical intervention on Protoporphyrin IX accumulation and biodistribution in normal skin following topical 5-aminolevulinic acid at high and low vehicle viscosity
    Medical condition: Healthy skin on the upper back on 3 participants in study a and 12 participants in study b.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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